EOSIOPHIL AND BASOPHIL REACTIONS

   Autistic children appear to have an increased eosinophil and basophil response to IgE-mediated reactions, which could explain the high prevalence of allergic disorders among autistic children. (Bidet et al, 1993; Renzoni et al, 1995)

   The number of eosinophils in the blood decrease with T3 or T4 treatment (Steinsapir et al, 1982), clearly indicating thyroid hormone involvement.

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Bidet B, Leboyer M, Descours B, Bouvard MP, Benveniste J - "Allergic sensitization in infantile autism" J Autism Dev Disord 23(2):419-20(1993) http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&uid=8331059&Dopt=r

Renzoni E, Beltrami V, Sestini P, Pompella A, Menchetti G, Zapella  M - "Brief report: allergological evaluation of children with autism" J Autism
Dev Disord 25(3):327-33(1995)
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&uid=7559298&Dopt=r

Steinsapir J, Rojas AM, Mena M, Tchernitchin AN - "Effects of thyroid hormone on some uterine responses to estrogen" Endocrinology 110(5):1773-9 (1982) http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7075537&form=6&db=m&Dopt=r